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vortioxetine (Trintellix – formerly known as Brintellix)

vortioxetine (Trintellix – formerly known as Brintellix)

What is vortioxetine, and how does it work (mechanism of action)? Vortioxetine (Trintellix) is an antidepressant used for treating a certain type of depression known as major depressive disorder (MDD). Vortioxetine decreases the reuptake of serotonin just like selective serotonin reuptake inhibitors (SSRIs). It also stimulates various serotonin receptors in the brain. The exact mechanism […]

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desvenlafaxine (Pristiq, Khedezla)

desvenlafaxine (Pristiq, Khedezla)

What is desvenlafaxine (Pristiq), and how does it work (mechanism of action)? Desvenlafaxine is an oral drug that is used for treating depression. It is in a class of antidepressant drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRI); a class that also contains venlafaxine (Effexor) and duloxetine (Cymbalta). (Desvenlafaxine is an active metabolite of […]

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doxepin (Sinequan and Adapin are discontinued brand in the US; Silenor)

doxepin (Sinequan and Adapin are discontinued brand in the US; Silenor)

What is doxepin? What is doxepin used for? Doxepin belongs to a class of drugs called tricyclic antidepressants (TCAs) that are used primarily to treat depression and anxiety. Other examples of TCAs include amitriptyline (Elavil), nortriptyline (Pamelor), desipramine (Norpramin), and several others. Depression is an all-pervasive sense of sadness and gloom. In some patients with […]

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venlafaxine, Effexor XR (Effexor has been discontinued in the US)

venlafaxine, Effexor XR (Effexor has been discontinued in the US)

What is venlafaxine, and how does it work (mechanism of action)? Venlafaxine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for treating depression. Other drugs in this class include milnacipran (Savella), duloxetine (Cymbalta), and desvenlafaxine (Pristiq). Venlafaxine affects neurotransmitters, the chemicals that nerves within the brain make and release in order to communicate […]

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dronabinol (Marinol, THC)

dronabinol (Marinol, THC)

What is dronabinol-oral, and how does it work (mechanism of action)? Dronabinol (Marinol) is a man-made compound that contains cannabinoids found in the marijuana plant (Cannabis sativa L). Dronabinol contains tetrahydrocannabinol (THC) in standardized concentrations and does not contain other compounds found in street marijuana that is not approved by the FDA for medical use. […]

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Melanoma

Melanoma

Melanoma Symptoms and Signs Melanoma is a type of skin cancer that forms in pigment-forming cells (melanocytes). (A mole, or melanocytic nevus, is a benign tumor of these pigment-forming cells.) Melanoma is the most serious type of skin cancer. Rarely, melanomas can be found in other areas of the body that contain pigment-forming cells, including […]

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Childhood Brain Tumor Survivors Face More Struggles

Childhood Brain Tumor Survivors Face More Struggles

Latest Cancer News TUESDAY, June 25, 2019 (HealthDay News) — Adult survivors of childhood brain tumors often face intellectual and financial struggles, a new study finds. Advances in treatment have prolonged the lives of many childhood brain tumor patients, but survivors may have to contend with a number of effects from the disease and its […]

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etodolac, Lodine (Discontinued)

What is etodolac? What is etodolac used for? Etodolac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin, Advil, Nuprin, etc.), naproxen (Aleve, Naprosyn), indomethacin (Indocin), nabumetone (Relafen) and numerous others. These drugs are used for the management of mild to moderate pain, fever, and […]

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phenylbutazone (Butazolidine)

What is phenylbutazone, and how does it work (mechanism of action)? Phenylbutazone is prescribed to treat inflammation and pain that results from ankylosing spondylitits, rheumatoid arthritis, gout, and osteoarthritis. Phenylbutazone has been removed from the United States market due to the availability of newer drugs with less adverse effects. Phenylbutazone is a nonsteroidal anti-inflammatory drug […]

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Rheumatoid Arthritis (RA)

REFERENCES: Bossini-Castillo, L., et al. “A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides.” Annals of the Rheumatic Diseases 74 (2015): e15. Costenbader, Karen H., and Elizabeth W. Karlson. “Epstein-Barr Virus and Rheumatoid Arthritis: Is There a Link?” Arthritis Res Ther 8.1 (2006): 204. Crane, M.M., et al. “Epidemiology and Treatment of […]