What is lisinopril and hydrochlorothiazide, and how does it work (mechanism of action)?

Zestoretic and Prinzide are combinations of two drugs, lisinopril and hydrochlorothiazide which are used for treating high blood pressure. For more information about each individual drug, please read the articles about lisinopril and hydrochlorothiazide.

What brand names are available for lisinopril and hydrochlorothiazide?


Is lisinopril and hydrochlorothiazide available as a generic drug?


Do I need a prescription for lisinopril and hydrochlorothiazide?


What is the dosage for lisinopril and hydrochlorothiazide?

The dose of Zestoretic or Prinzide is tailored to the patient’s individual need, based on each component of the medication.

Which drugs or supplements interact with lisinopril and hydrochlorothiazide?

Please read the lisinopril and hydrochlorothiazide articles.


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Is lisinopril and hydrochlorothiazide safe to take if I’m pregnant or breastfeeding?

Please read the lisinopril and hydrochlorothiazide articles. Please read the lisinopril and hydrochlorothiazide articles.

What else should I know about lisinopril and hydrochlorothiazide?

What preparations of lisinopril and hydrochlorothiazide are available?

Tablets: 12.5/10, 12.5/20, and 25/20 mg hydrochlorothiazide/mg lisinopril.

How should I keep lisinopril and hydrochlorothiazide stored?

Zestoretic and Prinzide should be stored at 59 F to 86 F (15 C to 30 C) and protected from excessive light and humidity.

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Medically Reviewed on 7/24/2019



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