There have been 600 confirmed cases of Ebola and 347 confirmed deaths since early August in the Democratic Republic of the Congo, making it the second-largest and second deadliest outbreak of the disease in history.

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Since the ongoing outbreak was declared on Aug. 1, Ebola symptoms have been reported in 649 people in the northeastern provinces of North Kivu and Ituri, with 600 of those cases confirmed as Ebola, the country’s health ministry said Monday night, ABC News reported.

The fatality rate in the outbreak is about 61 percent. There have been 347 confirmed deaths from Ebola and 49 probable Ebola deaths, according to the ministry.

On average, about half of all Ebola patients die, but death rates have ranged from 25 to 90 percent in past outbreaks, according to the World Health Organization, ABC News reported.

The worst Ebola outbreak occurred in West Africa in 2014-16. There were 28,652 people infected and 11,325 deaths, according to the U.S. Centers for Disease Control and Prevention.

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