What are the uses for albendazole?

Albendazole is FDA approved for the treatment of the following parasitic infections:

  • Hydatid Disease Albendazole is used for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by dog tapeworm (Echinococcus granulosus) larvae.
  • Neurocysticercosis Albendazole is used to treat parenchymal neurocysticercosis due to active lesion caused by pork tapeworm (Taenia solium) larvae.
  • Off-label use Albendazole is also effective in treating infections caused by other parasites including Taenia saginata (beef tapeworm), Trichinella spiralis (pork worm), Trichuris trichiura (whipworm), Enterobius vermicularis (pinworm), Strongyloides stercoralis (threadworm), Ascaris lumbricoides (roundworm), Ancylostoma duodenale (hookworm), and Necator americanus (hookworm).

What brand names are available for albendazole?

Albenza

Is albendazole available as a generic drug?

No (beware of fraudulent suppliers)

Do I need a prescription for albendazole?

Yes

What are the side effects of albendazole?

Side effects which occurred with a frequency of = 1% include:

Side effects which occurred with a frequency of <1% include:

Other side effects of undefined frequency include:

  • aplastic anemia,
  • bone marrow suppression,
  • decrease in white blood count,
  • acute liver failure,
  • hepatitis, increase in liver enzymes,
  • severe skin rashes such as Steven-Johnson’s syndrome, and
  • acute kidney failure.

What is the dosage for albendazole?

The dosing of albendazole depends on which parasitic infection is being treated. When treating young children, tablets may be crushed or chewed and swallowed with a drink of water. Patients are advised to take albendazole with food.

Which drugs or supplements interact with albendazole?

Grapefruit juice may increase in blood levels of albendazole when administered concurrently. Fosphenytoin (Cerebyx) and phenytoin (Dilantin) decrease levels of albendazole by increasing its breakdown.

Is albendazole safe to take if I’m pregnant or breastfeeding?

There are no adequate clinical trials of albendazole administration during pregnancy. Albendazole should only be used during pregnancy if the potential benefit of treatment justifies the potential risk to the fetus. Albendazole has been classified FDA as pregnancy risk category C.

It is not known if albendazole is excreted in human milk. Due to the lack of safety data, albendazole should be used cautiously during breastfeeding.

What else should I know about albendazole?

What preparations of albendazole are available?

Tablets: 200 mg

How should I keep albendazole stored?

Tablets should be stored at room temperature between 20 C to 25 C (68 F to 77 F).

Medically Reviewed on 3/18/2019

References

Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine

REFERENCE:

FDA Prescribing Information.