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Genetics may determine severe alcohol withdrawal

Genetics may determine severe alcohol withdrawal

People with harmful drinking habits will likely experience withdrawal symptoms once they remove alcohol from their diets. Some individuals face much more intense — and sometimes dangerous — withdrawal symptoms than others, but why? A recent Yale-led investigation may have found the answer. A new study identifies the genetic predictors of severe alcohol withdrawal symptoms. […]

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Opioid crisis breakthrough: Non-addictive painkiller found effective

Opioid crisis breakthrough: Non-addictive painkiller found effective

Scientists have tested a non-addictive painkiller in primates and found it to be safe and effective. The fact that the compound was successful in a species so closely related to humans strengthens the findings, which could help solve the opioid public health crisis. A new and non-addictive painkiller may solve the U.S. opioid crisis. The […]

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Study provides further support for genetic factors underlying addictions

Study provides further support for genetic factors underlying addictions

Impairment of a particular gene raises increases susceptibility to opioid addiction liability as well as vulnerability to binge eating according to a new study. Dysfunction of the gene, casein kinase1-epsilon (CSNK1E), increases opioid’s euphoric response and produces a marked increase in sensitivity to binge eating in a female experimental model but not in the male. […]