What is mometasone, and how does it work (mechanism of action)?

Mometasone is a synthetic (man-made) glucocorticoid (steroid) that is used on the skin to relieve itching and inflammation of eczema, dermatitis, allergy and other skin rashes. The naturally-occurring glucocorticoid is cortisol or hydrocortisone which is produced in the body by the adrenal glands. Drugs within the same class as mometasone include betamethasone dipropionate (Diprosone), triamcinolone (Aristocort), diflorasone diacetate (Florone), and others. Application of glucocorticoids such as mometasone to the skin may suppress the body’s own production of cortisol by the adrenal glands; however mometasone and others within its class are considered intermediate in potency and are less likely to have this effect as compared to highly potent glucocorticoids. Mometasone works by suppressing inflammation and the immune response associated with inflammation. Mometasone was approved by the FDA in 1987.

What brand names are available for mometasone?

Elocon

Is mometasone available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for mometasone?

Yes

What are the side effects of mometasone?

The most commonly noted side effects associated with mometasone are:

  • stinging,
  • burning,
  • itching, and
  • irritation,

Dryness, or redness of the skin which may occur when this medication is first applied to the skin.

What is the dosage for mometasone?

To use mometasone cream or ointment, a thin film should be applied to the affected skin once daily. To apply the lotion, a few drops should be place on the affected areas once daily and massaged lightly until it disappears.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer

Which drugs or supplements interact with mometasone?

The combination of mometasone and anthralin topicals (used to treat psoriasis) should not be used since concomitant use may increase the symptoms of psoriasis. It is therefore advisable to discontinue topical steroids one week before starting anthralin.

Is mometasone safe to take if I’m pregnant or breastfeeding?

There are no adequate studies in pregnant women. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

It is not known if mometasone is secreted in breast milk therefore caution should be exercised when administered to a nursing woman.

What else should I know about mometasone?

What preparations of mometasone are available?

Ointment, cream, and lotion, all in a 0.1% concentration.

How should I keep mometasone stored?

All preparations should be kept between 2 C – 25 C (36 F – 77 F). The lotion should be shaken before each use.

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Medically Reviewed on 8/8/2019

References

Reference: FDA Prescribing Information