What are the side effects of ketorolac and ibuprofen?

Ketorolac

Common side effects from ketorolac include:

Rare side effects of ketorolac include:

Serious side effects of ketorolac include:

  • Stomach ulcers
  • Intestinal bleeding
  • Reduced kidney function
  • Liver failure

Other serious adverse events include:

  • NSAIDs reduce the ability of blood to clot and, therefore, increase bleeding after an injury. Ketorolac may cause ulcers and bleeding in the stomach and intestines, particularly with use for more than five days. Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Sometimes, the only signs or symptoms of bleeding may be:
  • NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously.
  • Liver failure has also been associated with ketorolac.
  • People who are allergic to aspirin and other NSAIDs should not use ketorolac.
  • Individuals with asthma or nasal polyps are more likely to experience allergic reactions to NSAIDs.

Ibuprofen

The most common side effects from ibuprofen are:

NSAIDs reduce the ability of blood to clot and, therefore, increase bleeding after an injury.

Ibuprofen may cause ulceration of the stomach or intestine, and the ulcers may bleed. Sometimes, ulceration can occur without abdominal pain; and due to bleeding, the only signs or symptoms of an ulcer may be black, tarry stools, weakness, and dizziness upon standing (orthostatic hypotension).

Sometimes, ulceration can occur without abdominal pain, due to the bleeding, and the only signs or symptoms of an ulcer are:

  • Black, tarry stools
  • Weakness
  • Dizziness upon standing (orthostatic hypotension)

NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients who already have impaired function of the kidney or congestive heart failure, and use of NSAIDs in these patients should be cautious.

People who are allergic to other NSAIDs, including aspirin, should not use ibuprofen.

Individuals with asthma are more likely to experience allergic reactions to ibuprofen and other NSAIDs.

Other serious side effects associated with NSAIDs are:

NSAIDs (except low-dose aspirin) may increase the risk of potentially fatal heart attacks, stroke, and related conditions in people with or without heart disease or risk factors for heart disease. The increased risk of heart attack or stroke may occur as early as the first week of use, and the risk may increase with longer use and is higher in patients who have underlying risk factors for heart and blood vessel disease. Therefore, NSAIDs should not be used for the treatment of pain resulting from coronary artery bypass graft (CABG) surgery.