What is glatiramer, and how does it work (mechanism of action)?

  • Glatiramer’s mechanism of action is not completely understood. Available data suggests that it may work by modifying immune processes by suppressing T-cells (white blood cells of the immune system) that cause inflammation and destruction of nerves in patients with MS . Glatiramer does not cure MS. It decreases the number of MS flares and lesions in the brain.
  • The FDA approved glatiramer in December, 1996.

What brand names are available for glatiramer-injection?

Copaxone, Glatopa

Is glatiramer available as a generic drug?


Do I need a prescription for glatiramer?


What are the uses for glatiramer?

Glatiramer is used for the treatment of patients with relapsing forms of multiple sclerosis (MS).

What are the side effects of glatiramer?

Common side effects include:

Other side effects include:

Possible serious side effects include:

What is the dosage for glatiramer?

  • The recommended dose for treating relapsing forms of MS is 20 mg injected under the skin daily or 40 mg injected under the skin 3 times a week (at least 48 hours apart).

Which drugs or supplements interact with glatiramer?

  • Drug interactions between glatiramer and other drugs have not been evaluated.
  • Available information does not suggest that glatiramer significantly interacts with other MS drugs. However, use of glatiramer with other drugs that also suppress the immune system may increase the risk of serious infection.

Is glatiramer safe to take if I’m pregnant or breastfeeding?

  • Glatiramer has not been adequately studied in pregnant women.
  • It is not known if glatiramer acetate is excreted in human milk.

What else should I know about glatiramer?

What preparations of glatiramer-injection are available?

Solution for injection: 20 mg/ml, 40 mg/ml in a single dose, prefilled syringe.

How should I keep glatiramer-injection stored?
  • Glatiramer should be stored refrigerated at 2 C to 8 C (36 F to 46 F).
  • It also may be stored at room temperature, 15 C to 30 C (59 F to 86 F) for one month if needed.
  • Frozen syringes should be discarded.


What kind of disease is multiple sclerosis? See Answer

Medically Reviewed on 8/26/2019



FDA Prescribing Information