Articles on Breast Cancer

How common is breast cancer?

Picture of breast cancer

Picture of breast cancer

Breast cancer is the most common non-skin cancer of American women, but it can also occur in men. Every year in the U.S., there are over 266,000 new diagnoses of breast cancer. A woman has a risk of one in eight for developing breast cancer at some point during her lifetime.

Are there early signs of breast cancer? How do I know if I have breast cancer?

  • There usually are no symptoms or signs of early breast cancer, but sometimes a mass or lump in the breast will be present.
  • Screening mammography first identifies many early breast cancers.
  • Breast cancer screening is important because it can usually identify the cancers at an early stage when treatments are likely to be effective and outcomes are better.

What causes breast cancer?

  • Doctors do not fully understand the exact cause of breast cancer, but we know that the risk of breast cancer increases as we age.
  • Other risk factors for breast cancer include a personal or family history of breast cancer and the presence of certain benign conditions in the breast.
  • People who have inherited certain genetic mutations (BRCA1, BRCA2) are also at increased risk of getting breast cancer and other cancers.

What is breast cancer?

Breast cancer is a malignant tumor (a collection of cancer cells) arising from the cells of the breast. Although breast cancer predominantly occurs in women, it can also affect men. This article deals with breast cancer in women. Breast cancer and its complications can affect nearly every part of the body.

What are the statistics on male breast cancer?

Breast cancer is rare in men (approximately 2,400 new cases diagnosed per year in the U.S.) but typically has a significantly worse outcome. This is partially related to the often late diagnosis of male breast cancer, when the cancer has already spread.

Symptoms and signs of breast cancer in men are similar to the signs and symptoms in women, with the most common symptom being a lump or change in skin of the breast tissue or nipple discharge. Although it can occur at any age, male breast cancer usually occurs in men over 60 years of age.

SLIDESHOW

Breast Cancer Diagnosis and Treatment See Slideshow

What are the different types of breast cancer? Where does breast cancer come from?

There are many types of breast cancer. Some are more common than others, and there are also combinations of cancers. Some of the most common types of cancer are as follows:

  • Ductal carcinoma in situ: The most common type of noninvasive breast cancer is ductal carcinoma in situ (DCIS). This early stage breast cancer has not spread and therefore usually has a very high cure rate.
  • Invasive ductal carcinoma: This cancer starts in the milk ducts of the breast and grows into other parts of the surrounding tissue. It is the most common form of breast cancer. About 80% of invasive breast cancers are invasive ductal carcinoma.
  • Invasive lobular carcinoma: This breast cancer starts in the milk-producing glands of the breast. Approximately 10% of invasive breast cancers are invasive lobular carcinoma.

The remainder of breast cancers are much less common and include the following:

  • Mucinous carcinoma are formed from mucus-producing cancer cells. Mixed tumors contain a variety of cell types.
  • Medullary carcinoma is an infiltrating breast cancer that presents with well-defined boundaries between the cancerous and noncancerous tissue.
  • Inflammatory breast cancer: This cancer makes the skin of the breast appear red and feel warm (giving it the appearance of an infection). These changes are due to the blockage of lymph vessels by cancer cells.
  • Paget’s disease of the nipple: This cancer starts in the ducts of the breast and spreads to the nipple and the area surrounding the nipple. It usually appears with crusting and redness around the nipple.
  • Adenoid cystic carcinoma: These cancers have both glandular and cystic features. They tend not to spread aggressively and have a good prognosis.
  • Lobular carcinoma in situ: This is not a cancer but an area of abnormal cell growth. This precancer can increase the risk of invasive breast cancer later in life.
  • Adenoid cystic carcinoma: These cancers have both glandular and cystic features. They tend not to spread aggressively and have a good prognosis.
  • Lobular carcinoma in situ: This is not a cancer but an area of abnormal cell growth. This precancer can increase the risk of invasive breast cancer later in life.

The following are other uncommon types of breast cancer:

  • Papillary carcinoma
  • Phyllodes tumor
  • Angiosarcoma
  • Tubular carcinoma

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Medically Reviewed on 12/11/2019

References

Kroener, L., D. Dumesic, and Z. Al-Safi. “Use of fertility medications and cancer risk: a review and update.” Curr Opin Obstet Gynecol May 22, 2017.

Salerno, K.E. “NCCN Guidelines Update: Evolving Radiation Therapy Recommendations for Breast Cancer.” J Natl Compr Canc Netw 15(5S) May 2017: 682-684.

Shield, Kevin D., et al. “Alcohol Use and Breast Cancer: A Critical Review.” Alcoholism: Clinical and Experimental Research Apr. 30, 2016.